Protein Labeling Reagents
Biotium Human Kappa Light Chain(L1C1), CF488A conjugate, 0.1mg/mL
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can gi
Biotium CD66 (CEA)(C66/261), CF568 conjugate, 0.1mg/mL
This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA positive) from pleural mesotheliomas (rarely or weakly CEA positive). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.Primary antibodies are available purified, or with a selection of fluorescent CF
Sigma Aldrich Fine Chemicals Biosciences Atto 488 NHS ester BioReagent, suitable for fluorescence, >=80% (coupling to amines) | 1MG
Atto 488 NHS ester BioReagent, suitable for fluorescence, >=80% (coupling to amines) | Purity: >=80% (coupling to amines) | 1MG
Biotium STEADY MEMBRANE STAIN KIT,500
CellBrite™ Steady Membrane Staining Kits •Full size kit (500 labelings): •CellBrite™ Steady Dye, 1000X in DMSO, 100 uL.•CellBrite™ Steady Enhancer, 1000X in DMSO, 100 uL.CellBrite™ Steady Membrane Staining Kits allow fluorescence imaging of cell surface for up to several days in culture. The CellBrite™ Steady Dyes are unique fluorescent membrane probes that distribute between the cell surface and intracellular compartments, so cells retain cell surface staining over time. With the use of CellBrite™ Steady Enhancer, intracellular staining can be reduced or eliminated for imaging of cell outlines or boundaries.
Cayman Chemical 2-hydroxy MyrIstIc AcId 10mg
A hydroxy fatty acid; inhibits cleavage between the enterovirus capsid proteins VP4 and VP2; inhibits Junin and Tacaribe viral replication (IC50s = 20.1 and 14.2 μM, respectively); previously characterized as a weak inhibitor of peptide myristoylation (Ki = 200 μM) but has been shown to be inactive in ARL1 cells when used at 100 μM